Emergency Evidence Updates – April 2025
Randomised Controlled Trials
0.9% Saline versus Ringer’s lactate as initial fluid in children with diabetic ketoacidosis: a double-blind randomized controlled trial BMJ Open Diabetes Research & Care
Effectiveness of Point-of-Care High-Sensitivity Troponin Testing in the Emergency Department: A Randomized Controlled Trial Annals of Emergency Medicine
Emergency Department Visits for Medication-Related Events With vs Without Pharmacist Intervention – The URGEIM Randomized Clinical Trial JAMA Internal Medicine
Paramedic analgesia comparing ketamine and morphine in trauma (PACKMaN): a randomised, double-blind, phase 3 trial The Lancet Regional Health Europe
Salbutamol for analgesia in renal colic: a prospective, randomised, placebo-controlled phase II trial Emergency Medicine Journal
The effect of audiovisual distraction on pain perception during reduction of distal radial fractures: A dual center randomized controlled trial The Journal of Emergency Medicine
NICE
Falls: assessment and prevention in older people and in people 50 and over at higher risk NG249
Molnupiravir for treating COVID-19 TA1056
Other Guidance/Reports
Definition, investigation and management of gastrointestinal dystonia in children and young people with neurodisability Archives of Disease in Childhood
ESTES recommendations for the treatment of polytrauma—a European consensus based on the German S3 guidelines for the treatment of patients with severe/multiple injuries European Journal of Trauma and Emergency Surgery
Imaging strategies for patients with multiple and/or severe injuries in the resuscitation room: a systematic review and clinical practice guideline update European Journal of Trauma and Emergency Surgery
Cochrane
Blood transfusion strategies for major bleeding in trauma
Primary Research
Prehospital
Appropriate cardiopulmonary resuscitation duration and predictors of return of spontaneous circulation in traumatic cardiac arrest BMC Emergency Medicine
Creation and validation of a roadside rescue skills scale for training pre-hospital medical teams: the RoadRes-Q scale Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Early clinical evaluation of a machine-learning system for risk prediction of trauma-induced coagulopathy in the prehospital setting Emergency Medicine Journal
Paramedic i-gel® Placement and Perception of Use in Prehospital Airway Management Prehospital Emergency Care
Patients discharged to police custody after paramedic evaluation: an observational cohort study Emergency Medicine Journal
Prehospital Ketamine Administration in Benzodiazepine Refractory Status Epilepticus: A Case Series Review Prehospital Emergency Care
The work system of prehospital medication administration: a qualitative mixed methods study with ambulance professionals BMC Emergency Medicine
“You treat your stress by doing what you’re supposed to do”: a qualitative inquiry into emotion regulation of paramedics and paramedic students in critical incidents BMC Emergency Medicine
General
Are acute asthma presentations to the emergency department an opportunity for optimising long-term management? A qualitative study on beliefs and behaviours of healthcare professionals Emergency Medicine Journal
Beyond Urgency: Emergency Nurse and Physician Perspectives on Nonurgent Emergency Department Use and the Role of Underlying Conditions Journal of Emergency Nursing
Decision analysis model of rapid versus deferred antibiotic initiation in patients with suspected sepsis in the emergency department Intensive Care Medicine
Goal-driven Timed Target Workflow: Optimizing the Workflow for Emergency Department to Inpatient Admission Journal of Emergency Nursing
How much time do nurses in Norwegian emergency departments spend on different work tasks with and without a clinical pharmacist present—a time and motion study BMC Emergency Medicine
Implementing “ER is for Emergencies” Practice Guideline to Reduce Nonemergent Emergency Department Visits Journal of Emergency Nursing
Intrathecal Dexamethasone as a FIRES Extinguisher: A 12-Patient Clinical Experience with Usage of Intrathecal Dexamethasone for Febrile Infection-Related Epilepsy Syndrome Neurocritical Care
Nurse Pediatric Competency, Certification, and Continuing Education: Impact on EDs’ Pediatric Readiness Journal of Emergency Nursing
The Implementation of Dynamic Appraisal of Situational Aggression Score at Emergency Department Triage Annals of Emergency Medicine
The relationship between workplace bullying and job stress among nurses working in emergency departments: a cross-sectional study BMC Emergency Medicine
Paediatrics
A Qualitative Study Exploring Adolescent and Caregiver Perspectives of Emergency Department Response After a Positive Suicide Screen Annals of Emergency Medicine
Blood product use in paediatric trauma: lessons from the TARN data Emergency Medicine Journal
Clinical Prediction Rules for Identifying Children With Testicular Torsion – A Multicenter Prospective Study Pediatric Emergency Care
Epidemiology of Pediatric Viral Illnesses Before, During, and After the “Tripledemic” Viral Surge Pediatric Emergency Care
Honey, I Shrank the Beads – Water Bead Growth and Shrinking in Different Solutions In Vitro Pediatric Emergency Care
Honey, I Shrank the Beads – Water Bead Growth and Shrinking in Different Solutions In Vitro Pediatric Emergency Care
Impact of an evidence-based sepsis pathway on paediatric hospital clinical practice: A quality improvement study Emergency Medicine Australasia
Liberalizing Maximum High-Flow Nasal Cannula Flow Rates in the General Inpatient Ward Is Associated With Decreased Intensive Care Admissions for Infants With Bronchiolitis Pediatric Emergency Care
Patient Age and Antibiotic Formulation Administration in the Pediatric Emergency Department Pediatric Emergency Care
Pediatric Cervical Spine Injuries – Lessons From a Rare Case of C5/C6 Facet Dislocation in an Adolescent With a Systematic Literature Review Pediatric Emergency Care
Pediatric head trauma algorithm for head CT decision-making in the emergency department Journal of Anesthesia, Analgesia and Critical Care
Pediatric Reference Ranges and Test Characteristics of E-point Septal Separation as a Marker for Left Ventricular Dysfunction – A Retrospective Study Pediatric Emergency Care
Performance of an Electronic Universal Mental Health Screening Tool in Pediatric Emergency Departments Pediatric Emergency Care
Predicting Intensive Care Utilization for Patients With MIS-C in the Emergency Department Pediatric Emergency Care
Psychiatric Emergency Service Use by Transgender and Gender-Diverse Youth Pediatric Emergency Care
Test characteristics of clinical findings and clinical decision rules for the diagnosis of septic arthritis in children with an acute limp presenting to the emergency department: a prospective observational study Emergency Medicine Journal
Upper Respiratory Infections and Respiratory Adverse Events and Interventions in Emergency Department Sedation of Children Annals of Emergency Medicine
Using a Clinical Pathway to Safely Reduce Transfers and Admissions for Croup in the Urgent Care Pediatric Emergency Care
Using feedback from paediatric resuscitation team members to improve quality of care Emergency Medicine Australasia
Adult
Association of Early Noninvasive Cardiac Stress Testing With Acute Myocardial Infarction and Mortality Annals of Emergency Medicine
Characterization of Patients with Symptoms of Gastroparesis Having Frequent Emergency Department Visits and Hospitalizations Clinical Gastroenterology and Hepatology
Emergency Nursing Care in a Patient With a Serum Blood Glucose of 2394 mg/dL: A Case Review Journal of Emergency Nursing
Factors associated with overall and high-risk return visits to the emergency department: a vital sign trajectory approach BMC Emergency Medicine
NeuroICU FastTrack: Rapid Disposition of Patients with Intracerebral Hemorrhage from the Emergency Department to Neuro-ICU Neurocritical Care
Nil Per Os in the Emergency Department: A Quantitative Study on Fasting Before Presumptive Emergency Surgery Journal of Emergency Nursing
Peri-intubation adverse events and clinical outcomes in emergency department patients: the BARCO study Critical Care
Potential length of stay reductions from emergency department use of a point-of-care high-sensitivity cardiac troponin assay: Pilot findings from Australia’s first cardiac emergency department Emergency Medicine Australasia
Real-time hemodynamic responses to epinephrine and their association with ROSC in out-of-hospital cardiac arrest Resuscitation
Rib Fractures after Chest Compressions for Cardiac Arrest: Retrospective Analysis of the AfterROSC1 and AfterROSC2 Multicenter Databases Resuscitation Plus
The Association Between Time to Completion of at Least 30 mL/kg and Hospital Outcomes Among Patients With Septic Shock Critical Care Explorations
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash
Excellent update! Clear, concise, and incredibly helpful for staying current with emergency medicine evidence. Thank you for the valuable insights!